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Table of Contents

Volume 63 Issue 7 October 1, 2016

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  • A survey of physicians trained in critical care medicine (CCM) and infectious diseases (ID) suggested this combination is synergistic and satisfying. However, most respondents had to train in individual specialties at separate institutions. Avenues for CCM-ID training should be considered.

  • We describe the first recognized clusters of transplant-transmitted Balamuthia mandrillaris. We describe the detection of this rare cause of encephalitis in each cluster, the clinical management and public health response, and recommendations to detect and defer potential donors with encephalitis.

  • We used social network analysis to demonstrate that Illinois healthcare facilities with the greatest network centrality were more likely to report higher carbapenem-resistant Enterobacteriaceae rates and should be considered as sites for augmented infection control interventions.

  • We developed a decision tree to predict the likelihood that a patient with bacteremia is infected with an extended-spectrum β-lactamase–producing organism. Evaluating 1288 bacteremic patients, our decision tree's positive and negative predictive values were 90.8% and 91.9%, respectively.

  • Patients who did not receive preferred beta-lactam therapy due to reported beta-lactam allergy had an increased number of adverse events compared with patients without reported history of beta-lactam allergy.

  • Borrelial lymphocytoma in adults is rare, predominantly located on the breast, often associated with erythema migrans, and usually caused by Borrelia afzelii. Fourteen-day antibiotic treatment, as used for erythema migrans, is effective.

  • In children and adolescents undergoing evaluation for Lyme disease, the C6 enzyme immunoassay had similar sensitivity but lower specificity than standard 2-tiered testing. This assay could be used to guide initial management decisions, but supplemental immunoblot should still be performed.

  • Preterm infants born to mothers with high cytomegalovirus (CMV) seroprevalence are as frequently infected as those born to mothers with lower seroprevalence. CMV infection contributes to an uneven clinical course, severe stages of retinopathy of prematurity (ROP), and even death.

  • Among hospitalized subjects exposed to antimicrobials, a high abundance of Lactobacillus spp. characterized the fecal microbiome of patients who did not acquire multidrug-resistant organisms during their hospitalization, consistent with a protective role for Lactobacillus spp.


  • We aimed to identify the diagnostic accuracy of the probe-to-bone test to diagnose diabetic foot osteomyelitis through a meta-analysis of the published literature. Our findings support the use of probe to bone as outlined by current guidelines.





  • The appropriate management of outpatient urinary tract infections is increasingly hampered by the issue of multidrug resistance. This review provides a framework for assessing the risk for resistance and for choosing an agent that is likely to be active based on existing data.


  • Projected growth of the HIV care provider workforce by 2019 will not accommodate the increase in HIV-infected persons requiring care. Ryan White Program–funded facilities may face provider attrition. Dissatisfaction with salary/reimbursement is substantial, and black and Hispanic providers are underrepresented.

  • Using national human immunodeficiency virus (HIV) surveillance data from 17 jurisdictions, 38% of HIV-diagnosed persons in care did not sustain viral suppression in 2012–2013, spending 60% and 30% of observation time with viral load above 200 and 10 000 copies/mL.

  • Serum concentrations of multiple inflammatory biomarkers strongly predict long-term mortality risk in human immunodeficiency virus–infected men receiving antiretroviral therapy with confirmed viral suppression. Results indicate several underlying inflammatory factors, 2 of which independently predict mortality risk.





For checked items

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

October 1, 2016

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Impact Factor: 8.886

5-Yr impact factor: 9.206

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