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Transmission of drug-resistant leprosy in Guinea-Conakry detected by molecular epidemiological approaches

  1. Roch Christian Johnsond
  1. aGlobal Health Institute, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
  2. bCentre national d'Appui à la lutte contre la Maladie (CNAM), Bamako, Mali
  3. cProgramme National Lèpre de Guinée, Guinea-Conakry
  4. dCIFRED University of Abomey-Calavi, Benin
  1. Corresponding author: Stewart T. Cole, PhD, Global Health Institute, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland (stewart.cole{at}


Molecular drug susceptibility testing was performed on skin biopsies from 24 leprosy patients from Guinea-Conakry for the first time. We identified primary drug-resistance in four cases and a dapsone-resistant cluster caused by the same strain. Primary transmission of drug-resistant Mycobacterium leprae, including a rifampicin-resistant strain, is reported.


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